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sting inhibitor c176  (MedChemExpress)


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    Structured Review

    MedChemExpress sting inhibitor c176
    Sting Inhibitor C176, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 172 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sting+inhibitor+c176/C-176/pm41259200-340-2-5
    Average 97 stars, based on 172 article reviews
    sting inhibitor c176 - by Bioz Stars, 2026-10
    97/100 stars

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    Related Articles

    other:

    Article Title: African swine fever virus infection enhances CD14-dependent phagocytosis of porcine alveolar macrophages to promote bacterial uptake and apoptotic body-mediated viral transmission.
    Article Snippet: NF-κB inhibitor BAY 11-7082 (HY-13453), cGAS inhibitor RU.521 (HY-114180), STING inhibitor C176 (HY-112906), TLR9 inhibitor E6446 (HY-12756), and bacterial adhesion inhibitor Sibofimloc (HY-12820) were purchased from MedChemExpress (Monmouth Month XXXX Volume 0 Issue 0 10.1128/jvi.00690-2518 D ow nl oa de d fr om h ttp s: //j ou rn al s. as m .o rg /jo ur na l/j vi o n 16 J un e 20 25 b y 15 0.

    Drug discovery:

    Article Title: Pharmacological inhibition of the cGAS-STING pathway suppresses microglia pyroptosis in sepsis-associated encephalopathy
    Article Snippet: .. Pyroptosis inhibitor DMF [ ] (purity:99.98%; catalogue no. HY-17363; CAS# 624-49-7), STING inhibitor C176 (purity: 99.45%; catalogue no. HY-112906; CAS#314054-00-7), and mitochondrial protectant idebenone (purity: 99.36%; catalogue no. HY-N0303; CAS#58186-27-9) were bought from MedChemExpress (MCE) compound library. ..

    Article Title: Pharmacological inhibition of the cGAS-STING pathway suppresses microglia pyroptosis in sepsis-associated encephalopathy.
    Article Snippet: .. Pyroptosis inhibitor DMF [30] (purity:99.98%; catalogue no. HY-17363; CAS# 624-49-7), STING inhibitor C176 (purity: 99.45%; catalogue no. HY-112906; CAS#31405400-7), and mitochondrial protectant idebenone (purity: 99.36%; catalogue no. HY-N0303; CAS#58186-27-9) were bought from MedChemExpress (MCE) compound library. ..

    ROS Assay:

    Article Title: Phospholipase A2 group IIA activates Indoleamine 2,3-dioxygenase 1 to drive the progression of pulmonary fibrosis.
    Article Snippet: Phospholipase A2 Group IIA (PLA2G2A), a secretory member of the phospholipase family, plays key roles in various physiological processes across multiple metabolic tissues.. While PLA2G2A is expressed in lung epithelial cells and fibroblasts, its functions in lung injury and fibrosis remain poorly understood.. In this study, we characterized the critical role of PLA2G2A in pulmonary fibrosis (PF) in both human patients and bleomycin (BLM)induced PF mouse models.

    Isolation:

    Article Title: Phospholipase A2 group IIA activates Indoleamine 2,3-dioxygenase 1 to drive the progression of pulmonary fibrosis.
    Article Snippet: Phospholipase A2 Group IIA (PLA2G2A), a secretory member of the phospholipase family, plays key roles in various physiological processes across multiple metabolic tissues.. While PLA2G2A is expressed in lung epithelial cells and fibroblasts, its functions in lung injury and fibrosis remain poorly understood.. In this study, we characterized the critical role of PLA2G2A in pulmonary fibrosis (PF) in both human patients and bleomycin (BLM)induced PF mouse models.

    DNA Extraction:

    Article Title: Phospholipase A2 group IIA activates Indoleamine 2,3-dioxygenase 1 to drive the progression of pulmonary fibrosis.
    Article Snippet: Phospholipase A2 Group IIA (PLA2G2A), a secretory member of the phospholipase family, plays key roles in various physiological processes across multiple metabolic tissues.. While PLA2G2A is expressed in lung epithelial cells and fibroblasts, its functions in lung injury and fibrosis remain poorly understood.. In this study, we characterized the critical role of PLA2G2A in pulmonary fibrosis (PF) in both human patients and bleomycin (BLM)induced PF mouse models.

    Infection:

    Article Title: Herpes simplex virus type 1 disseminates from the cornea to the CNS in mice by thwarting type III interferon immune defenses.
    Article Snippet: .. For the STING inhibitor C176 (MedChemExpress, HY-112906) treatment, WT mice were infected with or without 10 μL of HSV-1 WT (1.0 × 10 9 PFU) following corneal scratch and intraperitoneal injections of C176 (600 nmol per mouse) or PBS (control) at 0 and 12 h after infection. ..

    Article Title: Involvement of cGAS/STING Signaling in the Pathogenesis of Candida albicans Keratitis: Insights From Genetic and Pharmacological Approaches
    Article Snippet: .. To determine the effect of cGAS/STING signaling on FK development, the infected mice were subconjunctivally injected with STING inhibitor C176 (8-mM, 5 μL;, MedChem Express, Shanghai, China) or agonist diABZI (4-μM, 5μL; MedChem Express) on pre-infection day 2 and post-infection day 1, respectively. ..

    Control:

    Article Title: Herpes simplex virus type 1 disseminates from the cornea to the CNS in mice by thwarting type III interferon immune defenses.
    Article Snippet: .. For the STING inhibitor C176 (MedChemExpress, HY-112906) treatment, WT mice were infected with or without 10 μL of HSV-1 WT (1.0 × 10 9 PFU) following corneal scratch and intraperitoneal injections of C176 (600 nmol per mouse) or PBS (control) at 0 and 12 h after infection. ..

    Injection:

    Article Title: Involvement of cGAS/STING Signaling in the Pathogenesis of Candida albicans Keratitis: Insights From Genetic and Pharmacological Approaches
    Article Snippet: .. To determine the effect of cGAS/STING signaling on FK development, the infected mice were subconjunctivally injected with STING inhibitor C176 (8-mM, 5 μL;, MedChem Express, Shanghai, China) or agonist diABZI (4-μM, 5μL; MedChem Express) on pre-infection day 2 and post-infection day 1, respectively. ..



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